![]() ![]() ![]() The pathogenic form of this protein appears to be devoid of nucleic acids and supports its own amplification in the host. CWD and other TSEs are believed to be caused by a pathogenic effect on neurons of an abnormal isoform of a host-encoded glycoprotein, the prion protein. The only known natural hosts for CWD are deer ( Odocoileus species) and Rocky Mountain elk ( Cervus elaphus nelsoni) ( 1, 2). ![]() Chronic wasting disease (CWD) is classified as a transmissible spongiform encephalopathy (TSE), or prion disease, along with other animal diseases, such as scrapie and bovine spongiform encephalopathy.
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